About megatomi.com
About megatomi.com
Blog Article
Our new Obvious+ tissue clearing procedure is the only real method that delipidates samples without any modify in morphology and with small influence on structural integrity.
Megatome is a vibrating microtome made to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits higher-throughput tissue sectioning with uniform surface area profile, and minimal tissue hurt and knowledge reduction.
Antibodies may possibly just take weeks to diffuse through only a few millimeters of tissue, using a steep labeling gradient from floor to Main.
Megatome is created for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and incorporates a special deflection Management system.
SE uses a rotational electric powered industry to disperse highly electromobile molecules (which include antibodies or surfactant micelles) all over a porous sample without the need of damaging electrically billed structures within the tissue. This allows two-4 working day clearing of intact organs,
Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely clear. This allows gentle penetration to the sample and guarantees the acquisition of substantial-resolution, in-target image information.
Megatome is really a novel microtome that allows for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue problems and data decline.
It’s time for you to upgrade your microtome to Megatome. With precise significant-frequency slicing for an unmatched array of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous applications.
The SmartSPIM gentle sheet microscope offers unparalleled resolution and acquisition velocity through intact tissue volumes, although its modular structure lets you update and customize specific components.
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SHIELD avoids the variability of hydrogel megatomi.com embedding and the information reduction from PFA preservation, shielding specimens for multiple rounds of processing.
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